Virus-Host Interaction - Multiple Choice Questions

Q.) What is the most common way for a virus to kill a cell?

Dissolves the cellular membrane

Induces apoptosis via caspases

Totally blocks cellular transcription

Fragments cellular DNA

Q.) What happens during the 'incubation period'?

Virus replication happens at an intracellular level

This period commonly lasts for a few days

The virus is cleared from the body by the immune system

This period commonly lasts for a few hours

Q.) Papillomaviruses cause warts and cancer but how do they most often infect humans?

Are airborne

Via scratches and breaks in the skin

Are Nosocomial and spread in hospitals

Are water borne

Q.) Which of the following is the most special characteristic of the adaptive immune system?

Antibodies

Very rapid response to infection

Memory T cells

Clonal expansion of pre-existing antibodies and/or T cells

Q.) A special feature of adaptive immunity is:

Speed of response to a foreign protein

None of these

Ability to distinguish viruses and bacteria

Ability to distinguish self and non self

Q.) Many virus infections result in immune pathology, this is caused predominantly by which of the following?

A response of killer T cells (CD-8)

Antibody mediated reactions

A cytokine storm

A decline in function of the immune system

Q.) Interferons are very special defence mechanisms which operate by:

Binding to neighbouring cells

Inhibiting virus induced enzymes

Producing a long lasting state of resistance

Binding to viruses

Q.) Cytotoxic T cells can be activated via which of the following?

By releasing complement

By identifying virus peptides presented by antibodies

By reacting with budding viruses

By identifying virus peptides presented by MHC-I

Q.) Poliovirus can most easily become more virulent by which of the following processes?

Recombining with another enterovirus

Mutation of the RNA genome at only a few positions

Altering its protein coat

Multiple nucleotide deletions and substitutions

Q.) How are antibody producing cells stimulated?

Interacting with a plasma cell

Interacting with a virus short peptide

Interacting with a virus infected cell

Interacting with a T helper cell.