Virus-Host Interaction - Multiple Choice Questions

Q.) Interferons are very special defence mechanisms which operate by:

Binding to neighbouring cells

Inhibiting virus induced enzymes

Binding to viruses

Producing a long lasting state of resistance

Q.) How are antibody producing cells stimulated?

Interacting with a plasma cell

Interacting with a virus infected cell

Interacting with a T helper cell.

Interacting with a virus short peptide

Q.) Cytotoxic T cells can be activated via which of the following?

By identifying virus peptides presented by MHC-I

By releasing complement

By reacting with budding viruses

By identifying virus peptides presented by antibodies

Q.) What happens during the 'incubation period'?

This period commonly lasts for a few days

The virus is cleared from the body by the immune system

Virus replication happens at an intracellular level

This period commonly lasts for a few hours

Q.) A special feature of adaptive immunity is:

None of these

Ability to distinguish viruses and bacteria

Ability to distinguish self and non self

Speed of response to a foreign protein

Q.) What is the most common way for a virus to kill a cell?

Dissolves the cellular membrane

Induces apoptosis via caspases

Totally blocks cellular transcription

Fragments cellular DNA

Q.) Papillomaviruses cause warts and cancer but how do they most often infect humans?

Are airborne

Are Nosocomial and spread in hospitals

Via scratches and breaks in the skin

Are water borne

Q.) Which of the following is the most special characteristic of the adaptive immune system?

Very rapid response to infection

Memory T cells

Clonal expansion of pre-existing antibodies and/or T cells

Antibodies

Q.) Poliovirus can most easily become more virulent by which of the following processes?

Multiple nucleotide deletions and substitutions

Altering its protein coat

Recombining with another enterovirus

Mutation of the RNA genome at only a few positions

Q.) Many virus infections result in immune pathology, this is caused predominantly by which of the following?

Antibody mediated reactions

A response of killer T cells (CD-8)

A decline in function of the immune system

A cytokine storm