Virus-Host Interaction - Multiple Choice Questions

Q.) A special feature of adaptive immunity is:

Speed of response to a foreign protein

None of these

Ability to distinguish viruses and bacteria

Ability to distinguish self and non self

Q.) Many virus infections result in immune pathology, this is caused predominantly by which of the following?

A cytokine storm

A response of killer T cells (CD-8)

A decline in function of the immune system

Antibody mediated reactions

Q.) Poliovirus can most easily become more virulent by which of the following processes?

Multiple nucleotide deletions and substitutions

Altering its protein coat

Mutation of the RNA genome at only a few positions

Recombining with another enterovirus

Q.) What happens during the 'incubation period'?

Virus replication happens at an intracellular level

The virus is cleared from the body by the immune system

This period commonly lasts for a few hours

This period commonly lasts for a few days

Q.) Interferons are very special defence mechanisms which operate by:

Binding to neighbouring cells

Binding to viruses

Producing a long lasting state of resistance

Inhibiting virus induced enzymes

Q.) How are antibody producing cells stimulated?

Interacting with a virus infected cell

Interacting with a plasma cell

Interacting with a virus short peptide

Interacting with a T helper cell.

Q.) Cytotoxic T cells can be activated via which of the following?

By identifying virus peptides presented by antibodies

By releasing complement

By reacting with budding viruses

By identifying virus peptides presented by MHC-I

Q.) Papillomaviruses cause warts and cancer but how do they most often infect humans?

Are Nosocomial and spread in hospitals

Via scratches and breaks in the skin

Are water borne

Are airborne

Q.) Which of the following is the most special characteristic of the adaptive immune system?

Memory T cells

Clonal expansion of pre-existing antibodies and/or T cells

Very rapid response to infection

Antibodies

Q.) What is the most common way for a virus to kill a cell?

Fragments cellular DNA

Dissolves the cellular membrane

Totally blocks cellular transcription

Induces apoptosis via caspases