Virus-Host Interaction - Multiple Choice Questions

Q.) Papillomaviruses cause warts and cancer but how do they most often infect humans?

Are Nosocomial and spread in hospitals

Are water borne

Are airborne

Via scratches and breaks in the skin

Q.) Interferons are very special defence mechanisms which operate by:

Binding to viruses

Producing a long lasting state of resistance

Binding to neighbouring cells

Inhibiting virus induced enzymes

Q.) Poliovirus can most easily become more virulent by which of the following processes?

Multiple nucleotide deletions and substitutions

Recombining with another enterovirus

Mutation of the RNA genome at only a few positions

Altering its protein coat

Q.) Which of the following is the most special characteristic of the adaptive immune system?

Very rapid response to infection

Clonal expansion of pre-existing antibodies and/or T cells

Memory T cells

Antibodies

Q.) How are antibody producing cells stimulated?

Interacting with a virus infected cell

Interacting with a virus short peptide

Interacting with a T helper cell.

Interacting with a plasma cell

Q.) What happens during the 'incubation period'?

This period commonly lasts for a few hours

The virus is cleared from the body by the immune system

Virus replication happens at an intracellular level

This period commonly lasts for a few days

Q.) Cytotoxic T cells can be activated via which of the following?

By reacting with budding viruses

By identifying virus peptides presented by antibodies

By identifying virus peptides presented by MHC-I

By releasing complement

Q.) A special feature of adaptive immunity is:

Ability to distinguish self and non self

Ability to distinguish viruses and bacteria

Speed of response to a foreign protein

None of these

Q.) Many virus infections result in immune pathology, this is caused predominantly by which of the following?

Antibody mediated reactions

A response of killer T cells (CD-8)

A decline in function of the immune system

A cytokine storm

Q.) What is the most common way for a virus to kill a cell?

Induces apoptosis via caspases

Dissolves the cellular membrane

Fragments cellular DNA

Totally blocks cellular transcription