Virus-Host Interaction - Multiple Choice Questions

Q.) What happens during the 'incubation period'?

The virus is cleared from the body by the immune system

This period commonly lasts for a few days

Virus replication happens at an intracellular level

This period commonly lasts for a few hours

Q.) Cytotoxic T cells can be activated via which of the following?

By releasing complement

By reacting with budding viruses

By identifying virus peptides presented by antibodies

By identifying virus peptides presented by MHC-I

Q.) Poliovirus can most easily become more virulent by which of the following processes?

Multiple nucleotide deletions and substitutions

Recombining with another enterovirus

Altering its protein coat

Mutation of the RNA genome at only a few positions

Q.) A special feature of adaptive immunity is:

None of these

Ability to distinguish self and non self

Ability to distinguish viruses and bacteria

Speed of response to a foreign protein

Q.) Papillomaviruses cause warts and cancer but how do they most often infect humans?

Via scratches and breaks in the skin

Are Nosocomial and spread in hospitals

Are airborne

Are water borne

Q.) Which of the following is the most special characteristic of the adaptive immune system?

Antibodies

Clonal expansion of pre-existing antibodies and/or T cells

Memory T cells

Very rapid response to infection

Q.) How are antibody producing cells stimulated?

Interacting with a virus short peptide

Interacting with a T helper cell.

Interacting with a virus infected cell

Interacting with a plasma cell

Q.) Many virus infections result in immune pathology, this is caused predominantly by which of the following?

A response of killer T cells (CD-8)

Antibody mediated reactions

A cytokine storm

A decline in function of the immune system

Q.) What is the most common way for a virus to kill a cell?

Totally blocks cellular transcription

Induces apoptosis via caspases

Fragments cellular DNA

Dissolves the cellular membrane

Q.) Interferons are very special defence mechanisms which operate by:

Producing a long lasting state of resistance

Binding to neighbouring cells

Inhibiting virus induced enzymes

Binding to viruses