Virus-Host Interaction - Multiple Choice Questions

Q.) How are antibody producing cells stimulated?

Interacting with a virus infected cell

Interacting with a plasma cell

Interacting with a T helper cell.

Interacting with a virus short peptide

Q.) What is the most common way for a virus to kill a cell?

Fragments cellular DNA

Dissolves the cellular membrane

Induces apoptosis via caspases

Totally blocks cellular transcription

Q.) Poliovirus can most easily become more virulent by which of the following processes?

Recombining with another enterovirus

Altering its protein coat

Mutation of the RNA genome at only a few positions

Multiple nucleotide deletions and substitutions

Q.) A special feature of adaptive immunity is:

None of these

Ability to distinguish viruses and bacteria

Speed of response to a foreign protein

Ability to distinguish self and non self

Q.) Many virus infections result in immune pathology, this is caused predominantly by which of the following?

Antibody mediated reactions

A decline in function of the immune system

A response of killer T cells (CD-8)

A cytokine storm

Q.) Interferons are very special defence mechanisms which operate by:

Binding to neighbouring cells

Inhibiting virus induced enzymes

Binding to viruses

Producing a long lasting state of resistance

Q.) Which of the following is the most special characteristic of the adaptive immune system?

Clonal expansion of pre-existing antibodies and/or T cells

Very rapid response to infection

Memory T cells

Antibodies

Q.) What happens during the 'incubation period'?

This period commonly lasts for a few hours

The virus is cleared from the body by the immune system

Virus replication happens at an intracellular level

This period commonly lasts for a few days

Q.) Cytotoxic T cells can be activated via which of the following?

By identifying virus peptides presented by MHC-I

By reacting with budding viruses

By identifying virus peptides presented by antibodies

By releasing complement

Q.) Papillomaviruses cause warts and cancer but how do they most often infect humans?

Are water borne

Are Nosocomial and spread in hospitals

Via scratches and breaks in the skin

Are airborne